Stroke: Working toward a Prioritized World Agenda
Identifieur interne : 006E81 ( Main/Exploration ); précédent : 006E80; suivant : 006E82Stroke: Working toward a Prioritized World Agenda
Auteurs : Vladimir Hachinski ; Geoffrey A. Donnan ; Philip B. Gorelick ; Werner Hacke ; Steven C. Cramer ; Markku Kaste ; Marc Fisher ; Michael Brainin ; Alastair M. Buchan ; Eng H. Lo ; Brett E. Skolnick ; Karen L. Furie ; Graeme J. Hankey ; Miia Kivipelto ; John Morris ; Peter M. Rothwell ; Ralph L. Sacco ; Sidney C. Smith Jr. ; Yulun Wang ; Alan Bryer ; Gary A. Ford ; Costantino Iadecola ; Sheila C. O. Martins ; Jeff Saver ; Veronika Skvortsova ; Mark Bayley ; Martin M. Bednar ; Pamela Duncan ; Lori Enney ; Seth Finklestein ; Theresa A. Jones ; Lalit Kalra ; Jeff Kleim ; Ralph Nitkin ; Robert Teasell ; Cornelius Weiller ; Bhupat Desai ; Mark P. Goldberg ; Wolf-Dieter Heiss ; Osmo Saarelma ; Lee H. Schwamm ; Yukito Shinohara ; Bhargava Trivedi ; Nils Wahlgren ; Lawrence K. Wong ; Antoine Hakim ; Bo Norrving ; Stephen Prudhomme ; Natan M. Bornstein ; Stephen M. Davis ; Larry B. Goldstein ; Didier Leys ; Jaakko TuomilehtoSource :
- Cerebrovascular Diseases (Basel, Switzerland) [ 1015-9770 ] ; 2010.
Abstract
The aim of the Synergium was to devise and prioritize new ways of accelerating progress in reducing the risks, effects, and consequences of stroke.
Preliminary work was performed by 7 working groups of stroke leaders followed by a synergium (a forum for working synergistically together) with approximately 100 additional participants. The resulting draft document had further input from contributors outside the synergium.
Recommendations of the Synergium are:
To accelerate progress in stroke, we must reach beyond the current status scientifically, conceptually, and pragmatically. Advances can be made not only by doing, but ceasing to do. Significant savings in time, money, and effort could result from discontinuing practices driven by unsubstantiated opinion, unproven approaches, and financial gain. Systematic integration of knowledge into programs coupled with careful evaluation can speed the pace of progress.
Url:
DOI: 10.1159/000315099
PubMed: 20516682
PubMed Central: 3221270
Affiliations:
Links toward previous steps (curation, corpus...)
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Le document en format XML
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<author><name sortKey="Hachinski, Vladimir" sort="Hachinski, Vladimir" uniqKey="Hachinski V" first="Vladimir" last="Hachinski">Vladimir Hachinski</name>
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<author><name sortKey="Gorelick, Philip B" sort="Gorelick, Philip B" uniqKey="Gorelick P" first="Philip B." last="Gorelick">Philip B. Gorelick</name>
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<author><name sortKey="Hacke, Werner" sort="Hacke, Werner" uniqKey="Hacke W" first="Werner" last="Hacke">Werner Hacke</name>
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<author><name sortKey="Cramer, Steven C" sort="Cramer, Steven C" uniqKey="Cramer S" first="Steven C." last="Cramer">Steven C. Cramer</name>
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<author><name sortKey="Brainin, Michael" sort="Brainin, Michael" uniqKey="Brainin M" first="Michael" last="Brainin">Michael Brainin</name>
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<author><name sortKey="Buchan, Alastair M" sort="Buchan, Alastair M" uniqKey="Buchan A" first="Alastair M." last="Buchan">Alastair M. Buchan</name>
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<author><name sortKey="Hankey, Graeme J" sort="Hankey, Graeme J" uniqKey="Hankey G" first="Graeme J." last="Hankey">Graeme J. Hankey</name>
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<author><name sortKey="Kivipelto, Miia" sort="Kivipelto, Miia" uniqKey="Kivipelto M" first="Miia" last="Kivipelto">Miia Kivipelto</name>
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<author><name sortKey="Morris, John" sort="Morris, John" uniqKey="Morris J" first="John" last="Morris">John Morris</name>
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<author><name sortKey="Rothwell, Peter M" sort="Rothwell, Peter M" uniqKey="Rothwell P" first="Peter M." last="Rothwell">Peter M. Rothwell</name>
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<author><name sortKey="Sacco, Ralph L" sort="Sacco, Ralph L" uniqKey="Sacco R" first="Ralph L." last="Sacco">Ralph L. Sacco</name>
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<author><name sortKey="Smith Jr, Sidney C" sort="Smith Jr, Sidney C" uniqKey="Smith Jr S" first="Sidney C." last="Smith Jr.">Sidney C. Smith Jr.</name>
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<author><name sortKey="Wang, Yulun" sort="Wang, Yulun" uniqKey="Wang Y" first="Yulun" last="Wang">Yulun Wang</name>
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<author><name sortKey="Bryer, Alan" sort="Bryer, Alan" uniqKey="Bryer A" first="Alan" last="Bryer">Alan Bryer</name>
</author>
<author><name sortKey="Ford, Gary A" sort="Ford, Gary A" uniqKey="Ford G" first="Gary A." last="Ford">Gary A. Ford</name>
</author>
<author><name sortKey="Iadecola, Costantino" sort="Iadecola, Costantino" uniqKey="Iadecola C" first="Costantino" last="Iadecola">Costantino Iadecola</name>
</author>
<author><name sortKey="Martins, Sheila C O" sort="Martins, Sheila C O" uniqKey="Martins S" first="Sheila C. O." last="Martins">Sheila C. O. Martins</name>
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<author><name sortKey="Saver, Jeff" sort="Saver, Jeff" uniqKey="Saver J" first="Jeff" last="Saver">Jeff Saver</name>
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<author><name sortKey="Skvortsova, Veronika" sort="Skvortsova, Veronika" uniqKey="Skvortsova V" first="Veronika" last="Skvortsova">Veronika Skvortsova</name>
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<author><name sortKey="Bayley, Mark" sort="Bayley, Mark" uniqKey="Bayley M" first="Mark" last="Bayley">Mark Bayley</name>
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<author><name sortKey="Bednar, Martin M" sort="Bednar, Martin M" uniqKey="Bednar M" first="Martin M." last="Bednar">Martin M. Bednar</name>
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<author><name sortKey="Duncan, Pamela" sort="Duncan, Pamela" uniqKey="Duncan P" first="Pamela" last="Duncan">Pamela Duncan</name>
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<author><name sortKey="Enney, Lori" sort="Enney, Lori" uniqKey="Enney L" first="Lori" last="Enney">Lori Enney</name>
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<author><name sortKey="Finklestein, Seth" sort="Finklestein, Seth" uniqKey="Finklestein S" first="Seth" last="Finklestein">Seth Finklestein</name>
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<author><name sortKey="Jones, Theresa A" sort="Jones, Theresa A" uniqKey="Jones T" first="Theresa A." last="Jones">Theresa A. Jones</name>
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<author><name sortKey="Kalra, Lalit" sort="Kalra, Lalit" uniqKey="Kalra L" first="Lalit" last="Kalra">Lalit Kalra</name>
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<author><name sortKey="Kleim, Jeff" sort="Kleim, Jeff" uniqKey="Kleim J" first="Jeff" last="Kleim">Jeff Kleim</name>
</author>
<author><name sortKey="Nitkin, Ralph" sort="Nitkin, Ralph" uniqKey="Nitkin R" first="Ralph" last="Nitkin">Ralph Nitkin</name>
</author>
<author><name sortKey="Teasell, Robert" sort="Teasell, Robert" uniqKey="Teasell R" first="Robert" last="Teasell">Robert Teasell</name>
</author>
<author><name sortKey="Weiller, Cornelius" sort="Weiller, Cornelius" uniqKey="Weiller C" first="Cornelius" last="Weiller">Cornelius Weiller</name>
</author>
<author><name sortKey="Desai, Bhupat" sort="Desai, Bhupat" uniqKey="Desai B" first="Bhupat" last="Desai">Bhupat Desai</name>
</author>
<author><name sortKey="Goldberg, Mark P" sort="Goldberg, Mark P" uniqKey="Goldberg M" first="Mark P." last="Goldberg">Mark P. Goldberg</name>
</author>
<author><name sortKey="Heiss, Wolf Dieter" sort="Heiss, Wolf Dieter" uniqKey="Heiss W" first="Wolf-Dieter" last="Heiss">Wolf-Dieter Heiss</name>
</author>
<author><name sortKey="Saarelma, Osmo" sort="Saarelma, Osmo" uniqKey="Saarelma O" first="Osmo" last="Saarelma">Osmo Saarelma</name>
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<author><name sortKey="Schwamm, Lee H" sort="Schwamm, Lee H" uniqKey="Schwamm L" first="Lee H." last="Schwamm">Lee H. Schwamm</name>
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<author><name sortKey="Shinohara, Yukito" sort="Shinohara, Yukito" uniqKey="Shinohara Y" first="Yukito" last="Shinohara">Yukito Shinohara</name>
</author>
<author><name sortKey="Trivedi, Bhargava" sort="Trivedi, Bhargava" uniqKey="Trivedi B" first="Bhargava" last="Trivedi">Bhargava Trivedi</name>
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<author><name sortKey="Wahlgren, Nils" sort="Wahlgren, Nils" uniqKey="Wahlgren N" first="Nils" last="Wahlgren">Nils Wahlgren</name>
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<author><name sortKey="Wong, Lawrence K" sort="Wong, Lawrence K" uniqKey="Wong L" first="Lawrence K." last="Wong">Lawrence K. Wong</name>
</author>
<author><name sortKey="Hakim, Antoine" sort="Hakim, Antoine" uniqKey="Hakim A" first="Antoine" last="Hakim">Antoine Hakim</name>
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<author><name sortKey="Norrving, Bo" sort="Norrving, Bo" uniqKey="Norrving B" first="Bo" last="Norrving">Bo Norrving</name>
</author>
<author><name sortKey="Prudhomme, Stephen" sort="Prudhomme, Stephen" uniqKey="Prudhomme S" first="Stephen" last="Prudhomme">Stephen Prudhomme</name>
</author>
<author><name sortKey="Bornstein, Natan M" sort="Bornstein, Natan M" uniqKey="Bornstein N" first="Natan M." last="Bornstein">Natan M. Bornstein</name>
</author>
<author><name sortKey="Davis, Stephen M" sort="Davis, Stephen M" uniqKey="Davis S" first="Stephen M." last="Davis">Stephen M. Davis</name>
</author>
<author><name sortKey="Goldstein, Larry B" sort="Goldstein, Larry B" uniqKey="Goldstein L" first="Larry B." last="Goldstein">Larry B. Goldstein</name>
</author>
<author><name sortKey="Leys, Didier" sort="Leys, Didier" uniqKey="Leys D" first="Didier" last="Leys">Didier Leys</name>
</author>
<author><name sortKey="Tuomilehto, Jaakko" sort="Tuomilehto, Jaakko" uniqKey="Tuomilehto J" first="Jaakko" last="Tuomilehto">Jaakko Tuomilehto</name>
</author>
</analytic>
<series><title level="j">Cerebrovascular Diseases (Basel, Switzerland)</title>
<idno type="ISSN">1015-9770</idno>
<idno type="eISSN">1421-9786</idno>
<imprint><date when="2010">2010</date>
</imprint>
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<front><div type="abstract" xml:lang="en"><sec><title>Background and Purpose</title>
<p>The aim of the Synergium was to devise and prioritize new ways of accelerating progress in reducing the risks, effects, and consequences of stroke.</p>
</sec>
<sec><title>Methods</title>
<p>Preliminary work was performed by 7 working groups of stroke leaders followed by a synergium (a forum for working synergistically together) with approximately 100 additional participants. The resulting draft document had further input from contributors outside the synergium.</p>
</sec>
<sec><title>Results</title>
<p>Recommendations of the Synergium are: <italic>Basic Science, Drug Development and Technology:</italic>
There is a need to develop: (1) New systems of working together to break down the prevalent ‘silo’ mentality; (2) New models of vertically integrated basic, clinical, and epidemiological disciplines; and (3) Efficient methods of identifying other relevant areas of science. <italic>Stroke Prevention:</italic>
(1) Establish a global chronic disease prevention initiative with stroke as a major focus. (2) Recognize not only abrupt clinical stroke, but subtle subclinical stroke, the commonest type of cerebrovascular disease, leading to impairments of executive function. (3) Develop, implement and evaluate a population approach for stroke prevention. (4) Develop public health communication strategies using traditional and novel (e.g., social media/marketing) techniques. <italic>Acute Stroke Management:</italic>
Continue the establishment of stroke centers, stroke units, regional systems of emergency stroke care and telestroke networks. <italic>Brain Recovery and Rehabilitation:</italic>
(1) Translate best neuroscience, including animal and human studies, into poststroke recovery research and clinical care. (2) Standardize poststroke rehabilitation based on best evidence. (3) Develop consensus on, then implementation of, standardized clinical and surrogate assessments. (4) Carry out rigorous clinical research to advance stroke recovery. <italic>Into the 21st Century: Web, Technology and Communications:</italic>
(1) Work toward global unrestricted access to stroke-related information. (2) Build centralized electronic archives and registries. <italic>Foster Cooperation Among Stakeholders</italic>
(large stroke organizations, nongovernmental organizations, governments, patient organizations and industry) to enhance stroke care. <italic>Educate and energize professionals, patients, the public and policy makers</italic>
by using a ‘Brain Health’ concept that enables promotion of preventive measures.</p>
</sec>
<sec><title>Conclusions</title>
<p>To accelerate progress in stroke, we must reach beyond the current status scientifically, conceptually, and pragmatically. Advances can be made not only by doing, but ceasing to do. Significant savings in time, money, and effort could result from discontinuing practices driven by unsubstantiated opinion, unproven approaches, and financial gain. Systematic integration of knowledge into programs coupled with careful evaluation can speed the pace of progress.</p>
</sec>
</div>
</front>
</TEI>
<affiliations><list></list>
<tree><noCountry><name sortKey="Bayley, Mark" sort="Bayley, Mark" uniqKey="Bayley M" first="Mark" last="Bayley">Mark Bayley</name>
<name sortKey="Bednar, Martin M" sort="Bednar, Martin M" uniqKey="Bednar M" first="Martin M." last="Bednar">Martin M. Bednar</name>
<name sortKey="Bornstein, Natan M" sort="Bornstein, Natan M" uniqKey="Bornstein N" first="Natan M." last="Bornstein">Natan M. Bornstein</name>
<name sortKey="Brainin, Michael" sort="Brainin, Michael" uniqKey="Brainin M" first="Michael" last="Brainin">Michael Brainin</name>
<name sortKey="Bryer, Alan" sort="Bryer, Alan" uniqKey="Bryer A" first="Alan" last="Bryer">Alan Bryer</name>
<name sortKey="Buchan, Alastair M" sort="Buchan, Alastair M" uniqKey="Buchan A" first="Alastair M." last="Buchan">Alastair M. Buchan</name>
<name sortKey="Cramer, Steven C" sort="Cramer, Steven C" uniqKey="Cramer S" first="Steven C." last="Cramer">Steven C. Cramer</name>
<name sortKey="Davis, Stephen M" sort="Davis, Stephen M" uniqKey="Davis S" first="Stephen M." last="Davis">Stephen M. Davis</name>
<name sortKey="Desai, Bhupat" sort="Desai, Bhupat" uniqKey="Desai B" first="Bhupat" last="Desai">Bhupat Desai</name>
<name sortKey="Donnan, Geoffrey A" sort="Donnan, Geoffrey A" uniqKey="Donnan G" first="Geoffrey A." last="Donnan">Geoffrey A. Donnan</name>
<name sortKey="Duncan, Pamela" sort="Duncan, Pamela" uniqKey="Duncan P" first="Pamela" last="Duncan">Pamela Duncan</name>
<name sortKey="Enney, Lori" sort="Enney, Lori" uniqKey="Enney L" first="Lori" last="Enney">Lori Enney</name>
<name sortKey="Finklestein, Seth" sort="Finklestein, Seth" uniqKey="Finklestein S" first="Seth" last="Finklestein">Seth Finklestein</name>
<name sortKey="Fisher, Marc" sort="Fisher, Marc" uniqKey="Fisher M" first="Marc" last="Fisher">Marc Fisher</name>
<name sortKey="Ford, Gary A" sort="Ford, Gary A" uniqKey="Ford G" first="Gary A." last="Ford">Gary A. Ford</name>
<name sortKey="Furie, Karen L" sort="Furie, Karen L" uniqKey="Furie K" first="Karen L." last="Furie">Karen L. Furie</name>
<name sortKey="Goldberg, Mark P" sort="Goldberg, Mark P" uniqKey="Goldberg M" first="Mark P." last="Goldberg">Mark P. Goldberg</name>
<name sortKey="Goldstein, Larry B" sort="Goldstein, Larry B" uniqKey="Goldstein L" first="Larry B." last="Goldstein">Larry B. Goldstein</name>
<name sortKey="Gorelick, Philip B" sort="Gorelick, Philip B" uniqKey="Gorelick P" first="Philip B." last="Gorelick">Philip B. Gorelick</name>
<name sortKey="Hachinski, Vladimir" sort="Hachinski, Vladimir" uniqKey="Hachinski V" first="Vladimir" last="Hachinski">Vladimir Hachinski</name>
<name sortKey="Hacke, Werner" sort="Hacke, Werner" uniqKey="Hacke W" first="Werner" last="Hacke">Werner Hacke</name>
<name sortKey="Hakim, Antoine" sort="Hakim, Antoine" uniqKey="Hakim A" first="Antoine" last="Hakim">Antoine Hakim</name>
<name sortKey="Hankey, Graeme J" sort="Hankey, Graeme J" uniqKey="Hankey G" first="Graeme J." last="Hankey">Graeme J. Hankey</name>
<name sortKey="Heiss, Wolf Dieter" sort="Heiss, Wolf Dieter" uniqKey="Heiss W" first="Wolf-Dieter" last="Heiss">Wolf-Dieter Heiss</name>
<name sortKey="Iadecola, Costantino" sort="Iadecola, Costantino" uniqKey="Iadecola C" first="Costantino" last="Iadecola">Costantino Iadecola</name>
<name sortKey="Jones, Theresa A" sort="Jones, Theresa A" uniqKey="Jones T" first="Theresa A." last="Jones">Theresa A. Jones</name>
<name sortKey="Kalra, Lalit" sort="Kalra, Lalit" uniqKey="Kalra L" first="Lalit" last="Kalra">Lalit Kalra</name>
<name sortKey="Kaste, Markku" sort="Kaste, Markku" uniqKey="Kaste M" first="Markku" last="Kaste">Markku Kaste</name>
<name sortKey="Kivipelto, Miia" sort="Kivipelto, Miia" uniqKey="Kivipelto M" first="Miia" last="Kivipelto">Miia Kivipelto</name>
<name sortKey="Kleim, Jeff" sort="Kleim, Jeff" uniqKey="Kleim J" first="Jeff" last="Kleim">Jeff Kleim</name>
<name sortKey="Leys, Didier" sort="Leys, Didier" uniqKey="Leys D" first="Didier" last="Leys">Didier Leys</name>
<name sortKey="Lo, Eng H" sort="Lo, Eng H" uniqKey="Lo E" first="Eng H." last="Lo">Eng H. Lo</name>
<name sortKey="Martins, Sheila C O" sort="Martins, Sheila C O" uniqKey="Martins S" first="Sheila C. O." last="Martins">Sheila C. O. Martins</name>
<name sortKey="Morris, John" sort="Morris, John" uniqKey="Morris J" first="John" last="Morris">John Morris</name>
<name sortKey="Nitkin, Ralph" sort="Nitkin, Ralph" uniqKey="Nitkin R" first="Ralph" last="Nitkin">Ralph Nitkin</name>
<name sortKey="Norrving, Bo" sort="Norrving, Bo" uniqKey="Norrving B" first="Bo" last="Norrving">Bo Norrving</name>
<name sortKey="Prudhomme, Stephen" sort="Prudhomme, Stephen" uniqKey="Prudhomme S" first="Stephen" last="Prudhomme">Stephen Prudhomme</name>
<name sortKey="Rothwell, Peter M" sort="Rothwell, Peter M" uniqKey="Rothwell P" first="Peter M." last="Rothwell">Peter M. Rothwell</name>
<name sortKey="Saarelma, Osmo" sort="Saarelma, Osmo" uniqKey="Saarelma O" first="Osmo" last="Saarelma">Osmo Saarelma</name>
<name sortKey="Sacco, Ralph L" sort="Sacco, Ralph L" uniqKey="Sacco R" first="Ralph L." last="Sacco">Ralph L. Sacco</name>
<name sortKey="Saver, Jeff" sort="Saver, Jeff" uniqKey="Saver J" first="Jeff" last="Saver">Jeff Saver</name>
<name sortKey="Schwamm, Lee H" sort="Schwamm, Lee H" uniqKey="Schwamm L" first="Lee H." last="Schwamm">Lee H. Schwamm</name>
<name sortKey="Shinohara, Yukito" sort="Shinohara, Yukito" uniqKey="Shinohara Y" first="Yukito" last="Shinohara">Yukito Shinohara</name>
<name sortKey="Skolnick, Brett E" sort="Skolnick, Brett E" uniqKey="Skolnick B" first="Brett E." last="Skolnick">Brett E. Skolnick</name>
<name sortKey="Skvortsova, Veronika" sort="Skvortsova, Veronika" uniqKey="Skvortsova V" first="Veronika" last="Skvortsova">Veronika Skvortsova</name>
<name sortKey="Smith Jr, Sidney C" sort="Smith Jr, Sidney C" uniqKey="Smith Jr S" first="Sidney C." last="Smith Jr.">Sidney C. Smith Jr.</name>
<name sortKey="Teasell, Robert" sort="Teasell, Robert" uniqKey="Teasell R" first="Robert" last="Teasell">Robert Teasell</name>
<name sortKey="Trivedi, Bhargava" sort="Trivedi, Bhargava" uniqKey="Trivedi B" first="Bhargava" last="Trivedi">Bhargava Trivedi</name>
<name sortKey="Tuomilehto, Jaakko" sort="Tuomilehto, Jaakko" uniqKey="Tuomilehto J" first="Jaakko" last="Tuomilehto">Jaakko Tuomilehto</name>
<name sortKey="Wahlgren, Nils" sort="Wahlgren, Nils" uniqKey="Wahlgren N" first="Nils" last="Wahlgren">Nils Wahlgren</name>
<name sortKey="Wang, Yulun" sort="Wang, Yulun" uniqKey="Wang Y" first="Yulun" last="Wang">Yulun Wang</name>
<name sortKey="Weiller, Cornelius" sort="Weiller, Cornelius" uniqKey="Weiller C" first="Cornelius" last="Weiller">Cornelius Weiller</name>
<name sortKey="Wong, Lawrence K" sort="Wong, Lawrence K" uniqKey="Wong L" first="Lawrence K." last="Wong">Lawrence K. Wong</name>
</noCountry>
</tree>
</affiliations>
</record>
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